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Post-Doc -Genève Mass spectrometry data analyst – Natural Extract characterization

Innovative data mining strategies for natural extracts metabolomics, natural products dereplication and bioactives identification.

Project description and key responsibilities
Plants and microorganisms are sources of potential biologically active compounds. Accumulated via secondary metabolism pathways, these potent chemicals could exhibit a wide variety of structures and physicochemical properties making their identification amongst hundreds of molecules present in natural extracts more complex. If data acquisition on natural extracts constituents is no longer considered an obstacle thanks to the latest development in terms of analytical platforms (e.g. ultra-high-performance chromatographic approaches, high-resolution mass spectrometry (HRMS)), data processing, however, still is a real barrier to efficient extracts characterization and rapid identification of potential new bioactive entities.

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